Fait mathématique: 4222 is the number of 13-hexes with bilateral symmetry.
Culture générale: 4222 is a number for which we're missing a fact (submit one to numbersapi at google mail!).
Date historique: July 23rd is the day in 1984 that Vanessa Williams becomes the first Miss America to resign when she surrenders her crown after nude photos of her appeared in Penthouse magazine.