Fait mathématique: 5464 is the number of subsets of {1,2,3,...,16} that have a sum divisible by 12.
Culture générale: 5464 is a number for which we're missing a fact (submit one to numbersapi at google mail!).
Date historique: December 16th is the day in 1497 that Vasco da Gama rounds the Cape of Good Hope, the point where Bartolomeu Dias had previously turned back to Portugal.